Letter to Editor

Myxedema coma in COVID-19

Yuichi Takashi* and Daiji Kawanami*

Published: 31 July, 2021 | Volume 5 - Issue 1 | Pages: 029-030

SARS-CoV-2 infection is associated with thyroid disorders. It has been reported that myxedema coma (MC) can be complicated with COVID-19. COVID-19-related thyroid disorders consist of a broad spectrum of thyroid dysfunction, from thyrotoxicosis to decompensated hypothyroidism. It is possible that both primary and central thyroid disorders are induced by COVID-19 due to systemic inflammatory and immune responses. We experienced two cases in which patients with COVID-19 developed MC with central hypothyroidism. It is likely that MC affected the severity of COVID-19. It is necessary to consider the existence of MC during SARS-CoV-2 infection. We propose the potential mechanisms.

Read Full Article HTML DOI: 10.29328/journal.acem.1001021 Cite this Article Read Full Article PDF


Myxedema; Coma; SARS-CoV-2; COVID-19; Cytokine release syndrome


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