Abstract

Case Report

Papillary thyroid cancer and cervical lymph mode metastases – optimal preoperative evaluation

George H Sakorafas*

Published: 16 February, 2021 | Volume 5 - Issue 1 | Pages: 011-013

Papillary thyroid cancer (PTC) is the most common subtype of thyroid cancer and a highly curable malignancy [1]. However, despite its excellent prognosis, cervical lymph node metastases (CLNMs) are present in a significant percentage of patients with papillary thyroid cancer (PTC) (upto 50% - 60%) [2].

Read Full Article HTML DOI: 10.29328/journal.acem.1001018 Cite this Article Read Full Article PDF

Keywords:

Thyroid; Cancer; Thyroidectomy; Metastases; Lymph nodes; Papillary; Lymph node dissection

References

  1. Siegel RL, Miller KD, Fuchs HE, Jemal A. Cancer statistics, 2021. CA Cancer J Clin. 2021; 71: 7-33. PubMed: https://pubmed.ncbi.nlm.nih.gov/33433946/
  2. Grant CS. Recurrence of papillary thyroid cancer after optimized surgery. Gland Surg. 2015; 4: 52-62. PubMed: https://pubmed.ncbi.nlm.nih.gov/25713780/
  3. Haugen BR, Alexander EK, Bible KC, Doherty GM, Mandel SJ, et al. 2015 American Thyroid Association Management Guidelines for Adult Patients with Thyroid Nodules and Differentiated Thyroid Cancer. Thyroid. 2016; 26: 1-133. PubMed: https://pubmed.ncbi.nlm.nih.gov/26462967/
  4. Sakorafas GH, Christodoulou S, Lappas C, Safioleas M. Preoperative Detection of Cervical Lymph Node Metastases in Papillary Thyroid Cancer: A Surgical Perspective. Onkologie 2009; 32: 762-766.
  5. Kim SK, Woo JW, Park I, Lee JH, Choe JH, et al. Computed Tomography-Detected Central Lymph Node Metastasis in Ultrasonography Node-Negative Papillary Thyroid Carcinoma: Is It Really Significant? Ann Surg Oncol. 2017; 24: 442-449. PubMed: https://pubmed.ncbi.nlm.nih.gov/27624581/
  6. Bongers PJ, Verzijl R, Dzingala M, Vriens MR, Yu E, et al. Preoperative Computed Tomography Changes Surgical Management for Clinically Low-Risk Well-Differentiated Thyroid Cancer. Ann Surg Oncol. 2019; 26: 4439-4444. PubMed: https://pubmed.ncbi.nlm.nih.gov/31583547/
  7. Wang H, Liu K, Ren J. Magnetic Resonance Imaging Characteristics of Papillary Thyroid Carcinoma for the Prediction of Cervical Central Compartment Lymph Node Metastasis. J Comput Assist Tomogr. 2019; 43: 963-969. PubMed: https://pubmed.ncbi.nlm.nih.gov/31162232/
  8. Jung JH, Kim CY, Hyun Son S, Kim DH, Jeong SY, et al. Preoperative Prediction of Cervical Lymph Node Metastasis Using Primary Tumor SUVmax on 18F-FDG PET/CT in Patients with Papillary Thyroid Carcinoma. PLoS One. 2015; 10: e0144152. PubMed: https://pubmed.ncbi.nlm.nih.gov/26636824/
  9. Xu Y, Wu D, Wu W, Jiang J, Xi C, et al. Diagnostic value of cytology, thyroglobulin, and combination of them in fine-needle aspiration of metastatic lymph nodes in patients with differentiated thyroid cancer: A systematic review and network meta-analysis. Medicine (Baltimore). 2019; 98: PubMed: https://pubmed.ncbi.nlm.nih.gov/31702649/

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